What Are The Common 6 Causes Of IVF Failure?

IVF failure

Usually, you see an expert when your conventional effort does not facilitate you to become a parent. On the advice of an IVF doctor in Delhi or your locality, you get ready for IVF as your fertility treatment. Before you move to have the IVF treatment, you should know all about it, such as the process, basic requirements, and IVF success and failure. 

Common causes that make IVF failure:

1. Egg quality 

The success of embryo implantation is around 50% if women undergoing the IVF treatment process are below 35. Women above 40 have only a 12% chance of embryo implantation success. 

With age, embryo implantation goes down. It happens due to poor egg quality. You (female) should be ready for a donor egg as you know your egg quality is poor and could result in IVF failure. No viability in eggs of older women is responsible for IVF failure.  

2. Embryo quality 

Embryo quality is one of the primary reasons for an IVF failure. Many embryos can’t implant after their transfer to the uterus due to flaws in the fertilisation or development process. Embryos looking good and healthy in the lab might have inner defects that cause failure. In some cases, the uterus of some females may not be receptive to embryos. Further, embryo health is not suitable for its proper development and growth. 

3. Ovarian response 

Sometimes, the ovaries of a female do not respond well to fertility treatments. And no proper response causes issues in the production and release of multiple eggs simultaneously. If your FHS levels are higher, you cannot produce enough eggs for screening and probable implantation. It is higher with you if you are above 35 years of age. 

4. Lifestyle factors 

Your sinful lifestyle is also a threat to the success of your IVF treatment. You have a higher chance of IVF failure if you are a heavy smoker, consume too many pegs of alcoholic beverages, have no proper eating habits, and live a sedentary life. Most fertility experts advise couples to quit smoking at least three months before treating their infertility. They advise couples to manage their weight, eat a healthy & balanced diet, exercise regularly, and stay aware of stress.     

5. Chromosomal issues 

Chromosomal abnormalities in the embryo are also a concern for IVF failure. Whether you conceive naturally or through medical intervention, chromosomal issues can lead you to have miscarriages or no implantation. After 30, women start having chromosomal issues. And by the mid-40s, around 75% of women of reproductive age face chromosomal abnormalities. In addition, there are chromosomal issues in a male’s sperm. However, the concern is lower than a female partner. 

Your doctor can suggest genetic tests like PGS to identify the issues in sperm or egg and offer a suitable option to facilitate your family expansion plan. You should follow your doctor’s instructions and cooperate with them to make your IVF treatment successful for you. 

6. Sperm quality 

Like eggs, the quality of sperm is equally essential in having a conception, whether it is natural or through IVF. Here sperm quality means sperm count, motility, shape, and function. For successful fertilisation and embryo implantation, you (male partner) should have enough healthy sperm in your semen. A semen analysis can help you know the quality and quantity of your sperm, and doctors can decide whether they are suitable for fertilisation or not. If not, the doctors can advise you on a donor egg program to ensure the success of the IVF treatment. 


IVF failure is caused by sperm quality, maternity age, egg quality, ovarian response, lifestyle, embryo quality, and chromosomal issues. You can make your IVF treatment successful by following your doctor’s instructions and adopting a healthy lifestyle, including diet, exercise, weight management, etc.    

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